
Technicon expanded Skeggs’ continuous-flow technology into sequential multiple analyzers (SMA and SMAC systems) in the late 1960s and 1970s, which allowed laboratories to perform panels of multiple biochemical tests simultaneously from a single blood sample. Grouping these specific seven tests together became routine clinical practice as automated multichannel machines became widespread.
Beyond engineering instruments, he conducted vital medical research at the VA Hospital in Cleveland. Alongside Joe Kahn, he successfully isolated and discovered Angiotensin I and II, and discovered the Angiotensin-Converting Enzyme (ACE). This breakthrough laid the groundwork for ACE inhibitors, which are now taken by millions globally to treat high blood pressure.
https://obits.cleveland.com/us/obituaries/cleveland/name/leonard-skeggs-obituary?id=17844025
