Dr. Louis Pasteur disproved spontaneous generation and showed that microbes cause decay and fermentation.

The Germ Theory of Disease: Pasteur shattered centuries of medical dogma by successfully refuting the theory of spontaneous generation. Using his famous swan-neck flask experiments, he proved that microorganisms exist in the environment and contaminate sterile solutions only when exposed to outside particles. This directly accelerated the adoption of hygiene and sterile procedures in 19th-century medicine.

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